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Job Responsibilities/崗位職責： 1.Be familiar with the application of analytical methods for ADCs, such as DAR, residual free drug, aggregation level, endotoxin, etc. 熟悉ADC質量分析的技術手段，例如DAR、游離藥物、聚集體、內(nèi)毒素檢測等； 2.Responsible for the quality analysis and data interpretation of ADC and linker-payload, including SEC, HIC, RP-HPLC, CE-SDS et al. Knowledge of ADC potency evaluation methods, as ELISA, SPR or Linker-payload characterization methods, nuclear magnetic resonance (NMR), mass spectrometry (MS), inductively coupled plasma mass spectrometry (ICP-MS)，and gas chromatography (GC), et al. are preferred. 負責ADC和毒素連接子（linker-payload）的質量分析和數(shù)據(jù)解讀，包括：SEC、HIC、RP-HPLC、CE-SDS等。了解ADC的活性評價方法例如：ELISA、SPR 或者Linker-payload的表征手段核磁共振（NMR）、質譜（MS）、電感耦合等離子體質譜（ICP-MS）、氣相色譜（GC）等分析方法者優(yōu)先； 3.Support quality research and analytical method development, validation, and transfer for ADC small molecule intermediates and ADC during process development, IND application, and early clinical stages. 支持ADC小分子中間體和ADC藥物在工藝開發(fā)、IND申報階段和早期臨床階段的質量研究和分析方法開發(fā)、確認與轉移； 4.ADC analysis related trouble-shooting. 解決出現(xiàn)的ADC分析方法的相關問題； 5.Maintain laboratory equipment and ensure compliance with safety, environmental, and quality standards. 維護實驗室設備，確保實驗操作符合安全、環(huán)境和質量標準。