體外ADME科研員(北京)
崗位描述:
百濟(jì)神州DMPK部門正在尋找一名有才華和上進(jìn)心的科研員加入團(tuán)隊(duì),該人選將專注于進(jìn)行體外吸收、分布、代謝和排泄(ADME)研究,并與快節(jié)奏的藥物研究團(tuán)隊(duì)合作,圍繞小分子的體外ADME特征提供科學(xué)的方向。
工作職責(zé):
- 與早研同事合作,評(píng)估化合物ADME性質(zhì),以支持藥物設(shè)計(jì)和構(gòu)效關(guān)系(SAR)的藥物化學(xué)研究。
- 獨(dú)立開展,分析和解釋體外ADME實(shí)驗(yàn),包括但不限于代謝穩(wěn)定性,滲透性,蛋白結(jié)合率,酶誘導(dǎo)/抑制,轉(zhuǎn)運(yùn)體和藥物相互作用評(píng)估。
- 獨(dú)立開發(fā)LC-MS/MS方法并處理體外樣品。
- 獨(dú)立操作、故障排除和維護(hù)LC-MS/MS設(shè)備。
- 在藥物研究中圍繞體外ADME策略,同時(shí)探索新的技術(shù)和方法。
任職要求:
- 藥代動(dòng)力學(xué)、藥物代謝、藥學(xué)等相關(guān)專業(yè)碩士及以上學(xué)位
- 在體外ADME方面具有豐富的實(shí)踐經(jīng)驗(yàn)
- 具有對(duì)細(xì)節(jié)的敏銳眼光和專注于明確研究結(jié)果的能力
- 良好的人際關(guān)系,溝通,解決問題和協(xié)作能力,在快節(jié)奏的環(huán)境中提供高質(zhì)量的結(jié)果
百濟(jì)神州全球勝任力
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●清晰溝通
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