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工作內(nèi)容： 1. Design and execute antibody optimization campaigns using various display technologies, with a preference for yeast display 使用各種展示技術(shù)設(shè)計(jì)和執(zhí)行抗體優(yōu)化活動(dòng)，首選酵母展示； 2. Perform a wide range of molecular biology techniques, including PCR, molecular cloning, site-directed mutagenesis, and library construction 執(zhí)行廣泛的分子生物學(xué)技術(shù)，包括PCR、分子克隆、定點(diǎn)突變和文庫(kù)構(gòu)建； 3. Develop, optimize, and perform various in vitro binding assays, including ELISA and FACS, for antibody hit screening and characterization 開發(fā)、優(yōu)化和執(zhí)行各種體外結(jié)合試驗(yàn)，包括ELISA和FACS，用于抗體命中篩查和鑒定； 4. Contribute to the engineering and optimization of lead antibody candidates to improve their therapeutic properties (e.g., affinity, specificity, developability) 為先導(dǎo)抗體候選物的工程和優(yōu)化做出貢獻(xiàn)，以改善其治療特性（如親和力、特異性、可開發(fā)性）； 5. Analyze, interpret, and present experimental data effectively within the team 在團(tuán)隊(duì)中有效地分析、解釋和呈現(xiàn)實(shí)驗(yàn)數(shù)據(jù)； 6. Maintain detailed and accurate experimental records 保持詳細(xì)準(zhǔn)確的實(shí)驗(yàn)記錄。 候選人要求： 1. A MS degree in biochemistry, bioengineering, molecular biology or a related field生物化學(xué)、生物工程、分子生物學(xué)或相關(guān)專業(yè)碩士學(xué)位； 2. At least 2 years of relevant post-graduate experience in antibody engineering, preferably in a biopharmaceutical industry setting至少2年抗體工程相關(guān)研究生經(jīng)驗(yàn)，最好在生物制藥行業(yè)工作經(jīng)驗(yàn)； 3. Proven hands-on experience in core molecular biology techniques, including PCR, DNA cloning, and mutagenesis 在核心分子生物學(xué)技術(shù)方面擁有豐富的實(shí)踐經(jīng)驗(yàn)，包括PCR、DNA克隆和誘變； 4. Demonstrated experience with at least one antibody display technology (e.g., yeast display, phage display, ribosome display, mRNA display), with a strong preference for yeast display 具有至少一種抗體展示技術(shù)（如酵母展示、噬菌體展示、核糖體展示、mRNA展示）的經(jīng)驗(yàn)，對(duì)酵母展示有強(qiáng)烈偏好； 5. Proficiency in a variety of antibody characterization techniques, including ELISA, flow cytometry (FACS), and other relevant assays (ideally BLI or SPR) 精通各種抗體表征技術(shù)，包括ELISA、流式細(xì)胞術(shù)（FACS）和其他相關(guān)檢測(cè)（最好是BLI或SPR）； 6. Experience in antibody engineering techniques (e.g., affinity maturation, humanization) is highly desirable 有抗體工程技術(shù)（如親和力成熟、人源化）經(jīng)驗(yàn)者尤佳； 7. Strong analytical and problem-solving skills with the ability to independently design experiments, interpret results, and troubleshoot technical issues 較強(qiáng)的分析和解決問題的能力，能夠獨(dú)立設(shè)計(jì)實(shí)驗(yàn)、解釋結(jié)果和解決技術(shù)問題 8. Proven ability to work effectively both independently and as part of a collaborative team 具備獨(dú)立工作和作為協(xié)作團(tuán)隊(duì)工作的能力； 9. Strong communication skills (written and verbal) with the ability to present data clearly and concisely 良好的溝通技巧（書面和口頭），能夠清晰簡(jiǎn)潔地呈現(xiàn)數(shù)據(jù)； 10. A proactive and results-oriented mindset with a passion for scientific innovation 積極主動(dòng)、注重成果的心態(tài)，對(duì)科學(xué)創(chuàng)新充滿熱情。